Protein Agonists, Antagonists and Activators

Estradiol (CAS: 50-28-2)

Catalog #：EBC51096

Estradiol (CAS: 50-28-2)

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Product Information

Synonym(s)

17β-Estradiol, 17β-Oestradiol, E2

Chemical Name

17β-Estra-1,3,5(10)-triene-3,17-diol

Application

Estradiol is an ER agonist and activator of PI 3-kinase

CAS Number

50-28-2

Purity

≥98.0%

Molecular Weight

272.38

Molecular Formula

C₁₈H₂₄O₂

SMILES

CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O

Target & IC50

Estrogen receptor: IC50 = 0.01 nM
MCF7: IC50 = 0.32 nM
ERα : IC50 = 0.57 nM

Solubility

DMSO: 27.2 mg/mL (100 mM)
Ethanol: 20.4 mg/mL (75 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Estradiol is the main sex hormone present in females and also present in males as an active metabolic product of testosterone. It is the major estrogen which impacts on reproductive and organs such as the bones in humans.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol