Protein Agonists, Antagonists and Activators

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EC 23 (CAS: 104561-41-3)

Catalog #：EBC51093

Datasheet

EC 23 (CAS: 104561-41-3)

SKU-Pack Size	Availability	Size	Price
EBC51093-1MG	In Stock	1mg	$103.50
EBC51093-5MG	In Stock	5mg	$178.50
EBC51093-10MG	In Stock	10mg	$253.50
EBC51093-25MG	In Stock	25mg	$553.50

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Product Information

Synonym(s)

AGN 190205, BASF-46928

Chemical Name

4-((5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethynyl)benzoic acid

Application

EC 23 is an ATRA analog with similar activity

CAS Number

104561-41-3

Purity

≥98.0%

Molecular Weight

332.44

Molecular Formula

C₂₃H₂₄O₂

SMILES

O=C(O)C1=CC=C(C#CC2=CC=C3C(C)(C)CCC(C)(C)C3=C2)C=C1

Target & IC50

Retinoic acid receptor alpha: EC5050 = 0.6 nM
Retinoic acid receptor gamma: EC5050 = 0.6 nM
Retinoic acid receptor beta: EC5050 = 0.3 nM

Solubility

DMSO: 250 mg/mL (752.02 mM)

Preparing Stock Solutions

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	3.0081 ml	15.0403 ml	30.0806 ml
5 mM	0.6016 ml	3.0081 ml	6.0161 ml
10 mM	0.3008 ml	1.5040 ml	3.0081 ml
50 mM	0.0602 ml	0.3008 ml	0.6016 ml

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description

EC 23 is a photostable synthetic analog of all-trans retinoic acid (ATRA). Retinoic Acid is vitamin A derivative that is an agonist for the retinoic acid receptors, which act as transcription factors that regulate the growth and differentiation of normal and malignant cells. It is reported to promote the differentiation of embryonic cells into motor neurons, pancreatic progenitors and cardiomyocytes.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol