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Doxycycline Hyclate (CAS: 24390-14-5)
Catalog #：EBC51092
Doxycycline Hyclate
(CAS: 24390-14-5)
  SKU-Pack Size Availability Size Price
EBC51092-1ML In Stock 1mL(10mM in DMSO) ￥590.00
EBC51092-1G In Stock 1g ￥390.00
EBC51092-5G In Stock 5g ￥990.00
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Product Information
Synonym(s) Doxycycline hydrochloride hemiethanolate hemihydrate, WC2031
Chemical Name (4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide hyclate
Application Doxycycline Hyclate is an antimicrobial tetracycline that acts as an inhibitor of MMP-1, MMP-8 and MMP-9
CAS Number 24390-14-5
Purity ≥99.0%
Molecular Weight 512.94
Molecular Formula C₂₂H₂₄N₂O₈•HCl
SMILES CC1C2C(C3C(C(=O)C(=C(C3(C(=O)C2=C(C4=C1C=CC=C4O)O)O)O)C(=O)N)N(C)C)O
Target & IC50 collagen synthesis: IC50 = 25 μM
MMP-8: IC50 = 30 μM
MMP-1: IC50 = 300 μM
Solubility DMSO : 240 mg/mL (467.89 mM)
H₂O : 13.89 mg/mL (27.08 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 1.9495 ml 9.7477 ml 19.4955 ml
5 mM 0.3899 ml 1.9495 ml 3.8991 ml
10 mM 0.1950 ml 0.9748 ml 1.9496 ml
50 mM 0.0390 ml 0.1950 ml 0.3899 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Doxycycline is a synthetic oxytetracycline broad-spectrum antibiotic, used to treat a variety of infections such as Lyme disease, Rickettsia, Brucella melitensis, Chlamydia pneumoniae, and others. It is also an inhibitor of matrix metalloproteases and useful in regulating inducible gene expression in Tet-ON/Off systems. 
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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