USA：(540) 808-3925
China：400-117-0038
Order@ebiocell.com
China
Shopping Cart
Sign in \ Register
Hot Search：
Location：Home > Biochemicals > Protein Inhibitors
Brefeldin A (CAS: 20350-15-6)
Catalog #：EBC51070
Brefeldin A (CAS: 20350-15-6)
  SKU-Pack Size Availability Size Price
EBC51070-1ML In Stock 1mL(10mM in DMSO) ￥590.00
EBC51070-5MG In Stock 5mg ￥590.00
EBC51070-10MG In Stock 10mg ￥990.00
EBC51070-50MG In Stock 50mg ￥3290.00
EBC51070-100MG In Stock 100mg ￥5290.00
If you want to get a larger packsize, Please contact your local distributor or
email us atinfo@ebiocell.com
Please Select The Country You Are In To Find Your Local Distributor.
北京美瑞克生物科技有限公司 Phone：  +86 010-62890160 / 13691184142(微信同号)
2 / F, 128 malianwa North Road, Haidian District, E-mail：   mrkbio@163.com 
China Beijing China Website： www.mrkbio.com
Product Information
Synonym(s) Ascotoxin, Cyanein, Decumbin, Synergisidin
Chemical Name (1R,2E,6S,10E,11aS,13S,14aR)-1,13-Dihydroxy-6-methyl-1,6,7,8,9,11a,12,13,14,14a-decahydro-4H-cyclopenta[f]oxacyclotridecin-4-one
Application Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking
CAS Number 20350-15-6
Purity ≥98.0%
Molecular Weight 280.36
Molecular Formula C₁₆H₂₄O₄
SMILES O[C@@H]1C[C@H]2[C@H](O)C=CC(=O)O[C@@H](C)CCCC=C[C@@H]2C1
Target & IC50 B-cell specific antigen receptor-induced NF-kB activation: IC50 = 420 nM
Solubility DMSO: 14 mg/mL (50 mM)
Ethanol: 2.8 mg/mL (10 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.5668 ml 17.8342 ml 35.6684 ml
5 mM 0.7134 ml 3.5668 ml 7.1337 ml
10 mM 0.3567 ml 1.7834 ml 3.5668 ml
50 mM 0.0713 ml 0.3567 ml 0.7134 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

Brefeldin A is a lactone antibiotic originating discovered in fungi capable of inhibiting protein transport from the endolasmic reticulum to the Golgi apparatus. It is reported to act on the guanine nucleotide exchange factor named GBF1 that mediates the formation of transport vesicles and the unfolded protein response can result in apoptosis in some cells.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
Antibodies
Primary Antibodies
Monoclonal Antibodies
Polyclonal Antibodies
Recombinant Antibodies
Secondary Antibodies
Antibody Panels
Biochemicals
Antibiotics
Protein Agonists, Antagonists and Activators
Protein Inhibitors
Protein Substrates
Stains, Dyes and Fluorescent Reagents
Other Biochemicals
Support Products
Cell Culture Related Agents
Specialty Cell Culture Media
Primary Cell Culture Media
Basal Cell Culture Media
Contact Us
Phone：919-816-2261
Fax：1-886-598-2438
Email：ebiocell@ebiocell.com
Address： Commercial Park West 2327 Englert Dr.
Room 101-5 Durham ,NC 27713
Copyright 2015 EbioCell, Inc. All Rights Reserved. 　备案号：津ICP备2022005142号-1