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(E,Z)-4-Hydroxytamoxifen (CAS: 68392-35-8)
Catalog #：EBC51057
(E,Z)-4-Hydroxytamoxifen
(CAS: 68392-35-8)
  SKU-Pack Size Availability Size Price
EBC51057-1ML In Stock 1mL(10mM in DMSO) ￥790.00
EBC51057-5MG In Stock 5mg ￥790.00
EBC51057-10MG In Stock 10mg ￥1090.00
EBC51057-50MG In Stock 50mg ￥4290.00
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Product Information
Synonym(s) 4-Hydroxytamoxifen, 4OH-tamoxifen, 4-monohydroxytamoxifen
Chemical Name (Z)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol
Application (E,Z)-4-Hydroxytamoxifen is a potent and selective estrogen receptor modulator
CAS Number 68392-35-8
Purity ≥98.0%
Molecular Weight 387.51
Molecular Formula C₂₆H₂₉NO₂
SMILES OC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1
Target & IC50 Estrogen receptor
Solubility DMSO: 71 mg/mL (183.2 mM)
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.5806 ml 12.9029 ml 25.8058 ml
5 mM 0.5161 ml 2.5806 ml 5.1612 ml
10 mM 0.2581 ml 1.2903 ml 2.5806 ml
50 mM 0.0516 ml 0.2581 ml 0.5161 ml
Shipping Gel Pack
Storage Store at -20°C
Research Use For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.
Product Description

(E,Z)-4-Hydroxytamoxifen is a modulator of the of the estrogen receptor, with tissue specific agonistic and antagonistic effects. 4-hydroxy Tamoxifen is the active metabolite of tamoxifen that is also generated in the liver by the CYP2D6 enzyme. It exhibits a greater potency than the parent compound and is reported to be cytostatic and prevent cancerous cells from dividing.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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