Other Biochemicals - (E,Z)-4-Hydroxytamoxifen (CAS: 68392-35-8)

(E,Z)-4-Hydroxytamoxifen (CAS: 68392-35-8)

Catalog #：EBC51057

(E,Z)-4-Hydroxytamoxifen
(CAS: 68392-35-8)

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Product Information

Synonym(s)

4-Hydroxytamoxifen, 4OH-tamoxifen, 4-monohydroxytamoxifen

Chemical Name

(Z)-4-(1-(4-(2-(dimethylamino)ethoxy)phenyl)-2-phenylbut-1-en-1-yl)phenol

Application

(E,Z)-4-Hydroxytamoxifen is a potent and selective estrogen receptor modulator

CAS Number

68392-35-8

Purity

≥98.0%

Molecular Weight

387.51

Molecular Formula

C₂₆H₂₉NO₂

SMILES

OC1=CC=C(/C(C2=CC=C(OCCN(C)C)C=C2)=C(C3=CC=CC=C3)\CC)C=C1

Target & IC50

Estrogen receptor

Solubility

DMSO: 71 mg/mL (183.2 mM)

Preparing Stock Solutions

Shipping

Gel Pack

Storage

Store at -20°C

Research Use

For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
(E,Z)-4-Hydroxytamoxifen is a modulator of the of the estrogen receptor, with tissue specific agonistic and antagonistic effects. 4-hydroxy Tamoxifen is the active metabolite of tamoxifen that is also generated in the liver by the CYP2D6 enzyme. It exhibits a greater potency than the parent compound and is reported to be cytostatic and prevent cancerous cells from dividing.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol