Antibiotics - Aphidicolin (CAS: 38966-21-1)

Aphidicolin (CAS: 38966-21-1)

Catalog #：EBC51015

Aphidicolin (CAS: 38966-21-1)

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Product Information
Synonym(s)	APC
Chemical Name	(3R,4R,4aR,6aS,8R,9R,11aS,11bS)-4,9-bis(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalene-3,9-diol
Application	Aphidicolin is a novel tetracyclic diterpene antibiotic and also a DNA synthesis inhibitor in eukaryotes.
CAS Number	38966-21-1
Purity	≥98.0%
Molecular Weight	338.48
Molecular Formula	C₂₀H₃₄O₄
SMILES	C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O
Solubility	DMSO: 50mg/mL methanol: 10mg/mL
Shipping	Gel Pack
Storage	Store at -20°C
Research Use	For Research Use Only. Not Intended for Diagnostic Or Therapeutic Use.

Product Description
Aphidicolin is a diterpene fungal metabolite that blocks the cell cycle at early S-phase. In addition, Aphidicolin is a tetracyclic diterpene antibiotic with antiviral and antimitotic properties. Aphidicolin was first isolated from Cephelosporium aphidicola. Aphidicolin is a specific inhibitor of DNA polymerase α and δ in eukaryotic cells and in some viruses of animal origin.

Specific Protocols

>>	Western Blotting Protocol	>>	Immunoprecipitation Protocol
>>	Immunohistochemistry Protocol	>>	Immunofluorescence Protocol
>>	Immunocytochemistry Protocol	>>	Flow Cytometry Protocol
>>	ChIP Protocol	>>	ELISA Protocol
>>	HPLC Protocol	>>	PCR Protocol