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(-)-Blebbistatin (CAS: 856925-71-8)
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Catalog #：EBC51005
Datasheet
(-)-Blebbistatin (CAS: 856925-71-8)
  SKU-Pack Size Availability Size Price
EBC51005-1ML In Stock 1mL(10mM in DMSO) ￥690.00
EBC51005-2MG In Stock 2mg ￥590.00
EBC51005-5MG In Stock 5mg ￥890.00
EBC51005-10MG In Stock 10mg ￥1190.00
EBC51005-25MG In Stock 25mg ￥2590.00
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Product Information
Synonym(s) (S)-(-)-Blebbistatin, (S)-(-)-Blebbistatin
Chemical Name 1-Phenyl-1,2,3,4-tetrahydro-4-hydroxypyrrolo[2.3-b]-7-methylquinolin-4-one
Application -(−)-Blebbistatin is an inhibitor of myosin II
CAS Number 856925-71-8
Purity ≥99%
Molecular Weight 292.33
Molecular Formula C₁₈H₁₆N₂O₂
SMILES CC1=CC=C(N=C(N(C2=CC=CC=C2)CC3)[C@]3(O)C4=O)C4=C1
Target & IC50 myosin II ATPase activity: IC50 = 5 μM
ATPase: IC50 = 2 μM
smooth muscle myosin: IC50 = 80 μM
Solubility DMSO: 29.2 mg/mL (100 mM）
Preparing Stock Solutions
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 3.4208 ml 17.1040 ml 34.2079 ml
5 mM 0.6842 ml 3.4208 ml 6.8416 ml
10 mM 0.3421 ml 1.7104 ml 3.4208 ml
50 mM 0.0684 ml 0.3421 ml 0.6842 ml
Shipping Gel Pack
Storage Store at -20° C
Research Use For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Product Description

(S)-(−)-Blebbistatin is a selective inhibitor of myosin II (MYH2). It also inhibits contraction of the cleavage furrow without disrupting of mitosis or the contractile ring assembly. (S)-(−)-Blebbistatin exhibits rapid and reversible blocking of cell blebbing, as well as disruption of directed cell migration and of cytokinesis in vertebrate cells.
Specific Protocols
>> Western Blotting Protocol >> Immunoprecipitation Protocol
>> Immunohistochemistry Protocol >> Immunofluorescence Protocol
>> Immunocytochemistry Protocol >> Flow Cytometry Protocol
>> ChIP Protocol >> ELISA Protocol
>> HPLC Protocol >> PCR Protocol
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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