|Please select the country you are in to find your local distributor.|
|Applications||WB, IP, IHC-P, IF/ICC, FC|
|Host / Isotype||Rabbit IgG|
|Specificity||AGR2 Rabbit Monoclonal Antibody detects endogenous levels of AGR2 protein.|
|Formulation||In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.|
|Storage||Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.|
|Research Use||For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.|
WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry
H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected
|Synonym(s)||AG2; GOB-4; HAG-2; XAG-2; PDIA17; HEL-S-116; HAG2; AG2 protein; hAG2; Secreted cement gland protein XAG2 homolog; AG-2; AGR-2; AGR2; GOB4; HAG2/R; HPC-8|
|Entrez Gene ID|
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression.
|Product Image Gallery|
Western blot analysis of extracts on different cells, using AGR2 Rabbit Monoclonal Antibody (EAB21705) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.