SKU-Pack Size | Availability | Size | Price | |
EAB21563-100UL | In Stock | 100ul | ¥2290.00 |
Please select the country you are in to find your local distributor. |
北京美瑞克生物科技有限公司 | Phone: +86 010-62890160 / 13691184142(微信同号) | |
2 / F, 128 malianwa North Road, Haidian District, | E-mail: mrkbio@163.com | |
China | Beijing China | Website: www.mrkbio.com |
Product Information | |
Applications | WB, IHC-P |
Species Reactivity | Human |
Host / Isotype | Mouse IgG1 |
Clonality | Monoclonal |
Applications Dilutions | WB=1:500-2000 IHC-P=1:100-500 |
MW (kDa) | 110 |
Conjugate | Unconjugate |
Specificity | c-Kit Mouse Monoclonal Antibody detects endogenous levels of c-Kit protein. |
Purification | Affinity purification |
Concentration | 1mg/ml |
Format | Liquid |
Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
Shipping | Gel Pack |
Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
Research Use | For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. |
Application Key WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IF-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry |
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Reactivity Key H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish Hr-Horse All-All Species Expected |
Product Bioinformatics | |
Synonym(s) | Bs; C-Kit; CD117; Fdc; Gsfsco1; Gsfsco5; Gsfsow3; KIT; PBT; SCFR; SCO1; SCO5; Sl; SOW3; Ssm; Tr-kit; |
Gene Aliases | KIT |
UniProt ID | |
Entrez Gene ID |
Product Description | |
This gene encodes a receptor tyrosine kinase. This gene was initially identified as a homolog of the feline sarcoma viral oncogene v-kit and is often referred to as proto-oncogene c-Kit. The canonical form of this glycosylated transmembrane protein has an N-terminal extracellular region with five immunoglobulin-like domains, a transmembrane region, and an intracellular tyrosine kinase domain at the C-terminus. Upon activation by its cytokine ligand, stem cell factor (SCF), this protein phosphorylates multiple intracellular proteins that play a role in in the proliferation, differentiation, migration and apoptosis of many cell types and thereby plays an important role in hematopoiesis, stem cell maintenance, gametogenesis, melanogenesis, and in mast cell development, migration and function. This protein can be a membrane-bound or soluble protein. Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous leukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. |
Product Image Gallery | |
Western blot analysis of extracts on different cells, using c-Kit Mouse Monoclonal Antibody (EAB21563) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Lane1: Jurkat Lane2: Hela Predicted band size: 110 kDa; Observed band size: 145 kDa Immunohistochemical analysis of paraffin-embedded Human gastrointestinal stromal tumor tissue, using c-Kit Mouse Monoclonal Antibody (EAB21563) at 1:200 dilution.
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Specific Protocols | |