Tacrolimus, also known as FK-506, is a macrolide isolated from the fungus Streptomyces tsukubaensis. Tacrolimus binds to the FKBP-12 protein and Forms a complex with calcium-dependent proteins, thereby inhibiting calcineurin phosphatase activity and resulting in decreased cytokine production. This agent exhibits potent immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation. Tacrolimus possesses similar immunosuppressive properties to cyclosporine, but is more potent. Check For active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). For the detailed information about the solubility of FK-506 (Tacrolimus) in water, the solubility of FK-506 (Tacrolimus) in DMSO, the solubility of FK-506 (Tacrolimus) in PBS buffer, the animal experiment（test） of FK-506 (Tacrolimus),the in vivo,in vitro and clinical trial test of FK-506 (Tacrolimus),the cell experiment（test） of FK-506 (Tacrolimus),the IC50, EC50 and Affinity of FK-506 (Tacrolimus), please contact DC Chemicals.