P01236

PRL (also designated Prolactin) is a 226 amino acid protein, plays a role in multiple processes, including cell growth, reproduction and immune function. Full-length Prolactin, as well as an alternative splice product lacking the third exon, are secreted by endothelial cells involved in angiogenesis. In addition to its role in mammary developmant and lactation, Prolactin is known to play a role in the development of mammary cancer, acting as both a mitogen and a differentiating agent. Prolactin has also been shown to enhance the proliferation of B cell hybridomas, leading to an overall increase in antibody production.