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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 76 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RIP/RIPK1 Rabbit Monoclonal Antibody detects endogenous levels of RIP/RIPK1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RIP also known as RIP1, RIPK1 is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. RIP protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIP functions as a key mediator in signaling pathways initiated by death receptors such as TNF receptor 1 (TNFR1) and Fas/CD95, leading to the activation of NF-κB and MAP kinases, which are important for inflammation, cell survival, and immune responses. The proper function of RIPK1 is vital, as dysregulation has been implicated in various pathological conditions including inflammatory diseases, neurodegenerative disorders, and cancer. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, THP-1, NIH/3T3 cells, using RIP/RIPK1 Rabbit Monoclonal Antibody (EAB22130) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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