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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IF/ICC | 79 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IF/ICC=1:50-200 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ACSS2/AceCS1 Rabbit Monoclonal Antibody detects endogenous levels of ACSS2/AceCS1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ACSS2 also known as AceCS1 is a 701 amino acid cytoplasmic protein that catalyzes the ATP-dependent activation of acetate to form acetyl-CoA, a key substrate for energy production and lipid biosynthesis. This enzymatic activity maintains energy homeostasis and supports various metabolic pathways, particularly in tissues with high energy demands such as the liver and kidney, where ACSS2 expression is most abundant. ACSS2 is regulated by unsaturated fatty acids and sterol regulatory element-binding proteins (SREBPs), highlighting its importance in lipid metabolism and cellular signaling. Human ACSS2 exists as two alternatively spliced isoforms and shares 93% sequence identity with its mouse counterpart, indicating a conserved functional role across species. |
