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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | IHC-P, IF/ICC, FC, ELISA | 29 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Emerin Mouse Monoclonal Antibody detects endogenous levels of Emerin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Emerin also known as EMD is a crucial component of the nuclear lamina. Emerin plays a significant role in maintaining the structural integrity of the nuclear envelope and facilitating chromatin organization. Emerin′s localization to the nuclear membrane is vital for proper nuclear function, as emerin helps anchor the nuclear lamina to the inner nuclear membrane, thereby influencing gene expression and cellular signaling pathways. Emerin′s specific localization to desmosomes and fasciae adherentes in cardiac tissue may explain the conduction defects observed in affected patients, highlighting emerin′s critical role in both muscle and cardiac health. |
