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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 47 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cleaved Caspase-5 p10 (Ser331) Rabbit Polyclonal Antibody detects endogenous levels of Caspase-5 p10 protein resulting from cleavage adjacent to Ser331. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Caspase-5 also known as CAPS5 is a member of the cysteine-aspartic acid protease (caspase) family. Caspase-5 play a significant role in the inflammatory response by cleaving pro-inflammatory cytokines, thereby facilitating their maturation and release. This function is particularly important in the context of immune responses and tissue homeostasis, as dysregulation of caspase activity can lead to various pathological conditions, including cancer and autoimmune diseases. The human Caspase-5 gene is located on chromosome 11q22.3 and is predominantly expressed in the brain, with notable levels in the lung, liver, and skeletal muscle, highlighting its potential involvement in both central and peripheral immune responses. |
