| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 38 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Acetyl-DNA polymerase beta (Lys72) Rabbit Polyclonal Antibody detects endogenous levels of DNA polymerase beta protein only when acetylated at Lys72. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
DNA polymerase beta also known as DNA pol β, POLB is a DNA polymerase involved in base excision and repair, also called gap-filling DNA synthesis. DNA polymerase beta plays a crucial role in DNA repair and replication, particularly in synthesizing short DNA fragments during single-strand break repair. DNA polymerase beta′s ability to accurately incorporate nucleotides maintains genomic integrity, as errors can lead to mutations and genomic instability, which are hallmarks of various diseases, including cancer. DNA polymerase beta also interacts with several proteins involved in DNA damage response, such as proliferating cell nuclear antigen (PCNA), which enhances processivity during DNA synthesis. |
