| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 48 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | FoxA2/HNF3β Rabbit Monoclonal Antibody detects endogenous levels of FoxA2/HNF3β protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
FoxA2 also known as HNF-3beta is a member of the forkhead class of DNA-binding proteins. FoxA2 plays a crucial role in regulating gene expression during both embryonic development and in adult tissues. As a pioneer transcription factor, FoxA2 can bind to condensed chromatin, thereby facilitating the access of other transcription factors and influencing the development and differentiation of essential organs such as the liver, pancreas, and lungs. FoxA2 is indispensable for endoderm formation during gastrulation and plays a significant role in maintaining metabolism and glucose homeostasis. Dysregulation of FoxA2 has been linked to various developmental disorders and diseases, including diabetes and certain cancers, highlighting its importance in both normal physiology and disease pathogenesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on SW620, HepG2 cells, using FoxA2/HNF3β Rabbit Monoclonal Antibody (EAB22594) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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