| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IP, IHC-P, IF/ICC, FC, ELISA | 44 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:5000-20000 IP=1:100-500 IHC-P=1:500-2000 IF/ICC=1:500-2000 FC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TSG101 Mouse Monoclonal Antibody detects endogenous levels of TSG101 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TSG101(Tumor susceptibility 101) is a multi-domain cytoplasmic protein and fundamental component of ESCRT complex I, which is intimately involved in regulating the trafficking of proteins throughout the endosomal compartment. TSG101 plays a crucial role in cellular processes as TSG101 is involved in the regulation of the endosomal sorting complex required for transport (ESCRT), which is essential for the degradation of membrane proteins and the regulation of cellular signaling pathways. This function is particularly important in tumor suppression, as proper functioning of the ESCRT machinery can prevent the accumulation of signaling molecules that promote cell proliferation and survival, thereby inhibiting tumorigenesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HEK293, Jurkat, K562 cells, using TSG101 Mouse Monoclonal Antibody (EAB22873) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human ovarian cancer tissue, using TSG101 Mouse Monoclonal Antibody (EAB22873) at 1:1000 dilution.
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