| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 47 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Sox11 Rabbit Monoclonal Antibody detects endogenous levels of Sox11 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Sox11 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. Sox11 plays a pivotal role in neural development. Sox11 contains a high mobility group (HMG) box DNA-binding domain, which is essential for function as a transcriptional regulator. Sox11 is crucial for the differentiation and maintenance of neural progenitor cells, influencing cell fate decisions during the development of the central nervous system. Proper functioning of Sox11 is vital, as dysregulation of Sox11 expression has been linked to various neurodevelopmental disorders and may contribute to the pathogenesis of certain cancers. With evolutionary conservation and significant role in developmental processes, Sox11 serves as an important marker for studying neural development and associated diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on SH-SY5Y, Y79 cells, using Sox11 Rabbit Monoclonal Antibody (EAB22931) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 47 kDa; Observed band size: 65 kDa |
