| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 47 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | ARP3 Rabbit Monoclonal Antibody detects endogenous levels of ARP3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ARP3 also known as ACTR3 is a crucial component of the ARP2/3 complex, which plays a vital role in actin polymerization, a process essential for various cellular functions including cell migration, adhesion, and the formation of cellular protrusions. The ARP2/3 complex facilitates the nucleation of new actin filaments, enabling the rapid reorganization of the cytoskeleton in response to extracellular signals. This dynamic restructuring is particularly important in processes such as chemotaxis, where cells must move toward chemical signals, and in the formation of lamellipodia and filopodia, which are critical for cell movement and shape changes. The interaction of ARP3 with other proteins, such as the WASP family, is essential for the activation of the ARP2/3 complex, highlighting ARP3′s role in linking signaling pathways to cytoskeletal dynamics. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, C6, K562 cells, using ARP3 Rabbit Monoclonal Antibody (EAB22696) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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