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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P | 59 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:50-200 |
|
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Estrogen Receptor β/ERβ Rabbit Monoclonal Antibody detects endogenous levels of Estrogen Receptor β/ERβ protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
ERβ (Estrogen Receptor β) also konwn as ESR2, NR3A2 is a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. ERβ plays a crucial role in mediating estrogen effects, particularly in regulating gene expression related to reproductive tissues and other physiological processes. Located primarily in the nucleus, ERβ can also associate with the cell membrane, allowing rapid activation upon estrogen exposure. This unique localization enables ERβ to participate in both genomic and non-genomic signaling pathways, influencing cellular responses to hormonal changes. ERβ′s ability to dimerize and interact with specific regulatory elements in target genes is essential for function, and research has shown differential activation by various ligands, leading to distinct biological outcomes. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293, SH-SY5Y cells, using Estrogen Receptor β/ERβ Rabbit Monoclonal Antibody (EAB22700) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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