| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IF/ICC | 41 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CXCR3 Rabbit Monoclonal Antibody detects endogenous levels of CXCR3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CXCR3 also known as IP10, MIGR is a critical member of the C-X-C chemokine receptor family. CXCR3 plays a crucial role in immune response by mediating chemotaxis and calcium mobilization in T lymphocytes in response to specific C-X-C chemokines such as IP-10 and MIG. This function directs the migration of activated T cells to sites of inflammation, contributing to the body′s defense mechanisms against pathogens and regulation of immune responses. CXCR3 is highly expressed in IL-2-activated T lymphocytes, underscoring its significance in adaptive immunity, while remaining absent in resting T lymphocytes, B lymphocytes, monocytes, and granulocytes, highlighting its role as a marker for activated immune cells. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using CXCR3 Rabbit Monoclonal Antibody (EAB22142) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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