| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 33 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Myelin Basic Protein/MBP Mouse Monoclonal Antibody detects endogenous levels of Myelin Basic protein/MBP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
MBP(Myelin Basic Protein) is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. MBP plays a crucial role in the formation and maintenance of the myelin sheath, which insulates nerve fibers and facilitates efficient signal transmission in the central nervous system. MBP′s structure is characterized by its highly basic nature, allowing interaction with negatively charged lipids in the myelin membrane, thereby stabilizing the myelin sheath. This structural integrity is vital for proper neuronal function, as disruptions in myelin can lead to severe neurological disorders, including multiple sclerosis. Furthermore, MBP undergoes post-translational modifications, such as phosphorylation, which are essential for regulating function and stability during myelinogenesis and in response to neuronal activity. |
| Product Image Gallery | |
 Western blot analysis of extracts on Mouse brain, Rat brain cells, using Myelin Basic Protein/MBP Mouse Monoclonal Antibody (EAB22059) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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