| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IF/ICC, ELISA | 49 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-IL-13Rα1 (Tyr405) Rabbit Polyclonal Antibody detects endogenous levels of IL-13Rα1 only when phosphorylated at Tyr405. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
IL-13Rα1 also known as CD213A1, IL13RA1 is a subunit of the interleukin 13 receptor. IL-13Rα1 plays a pivotal role in mediating the effects of the Th2 cytokine Interleukin-13 (IL-13), which is crucial for regulating immune responses, particularly in allergic reactions and asthma. IL-13R alpha 1 functions as part of a heterodimer with IL-4Rα, facilitating signaling pathways that lead to the activation of genes involved in inflammation and tissue remodeling. Expression of IL-13R alpha 1 is predominantly found in immune cells such as B cells, monocytes, and T cells, highlighting importance in immune regulation. The interaction between IL-13R alpha 1 and IL-4Rα is essential for IL-13′s biological activity, enhancing receptor affinity for the cytokine and amplifying the signaling cascade that contributes to allergic inflammation. |
| Product Image Gallery | |
 Western blot analysis of extracts on 293 cells treated with LPS, using Phospho-Mnk1 (Thr255) Rabbit Polyclonal Antibody (EAB14051) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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