Other Biochemicals - Hydrocortisone (CAS: 50-23-7)

Hydrocortisone (CAS: 50-23-7)

Catalog #：EBC52291

Biological Activity

Synonyms

Cortisporin Otico; Evacort; Cortisol; Cortenema; Timocort; Stiefcorcil; Incortin-hydrogen

Chemical Name

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one

Application

Hydrocortisone is a primary glucocorticoid and anti-inflammatory agent.

CAS Number

50-23-7

Purity

≥98%

Molecular Weight

362.46

Molecular Formula

C21H30O5

SMILES

C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O

Target & IC50

GR: IC50 = 26 nM
CYP3A4 : IC50 = >50000 nM

Shipping

Gel Pack

Storage

Store at 2-8°C

Preparing Stock Solutions

Molecular Structure

ConcentrationSolventMass	1 mg	5 mg	10 mg
1 mM	2.7589 ml	13.7946 ml	27.5893 ml
5 mM	0.5518 ml	2.7589 ml	5.5179 ml
10 mM	0.2759 ml	1.3795 ml	2.7589 ml
50 mM	0.0552 ml	0.2759 ml	0.5518 ml

Solubility
DMSO: 200 mg/mL (551.79 mM）

Product Description

Hydrocortisone is the primary glucocorticoid secreted by the adrenal cortex. Hydrocortisone has three times the anti-inflammatory potency of corticosterone but much lower Na+ retention potency.Hydrocortisone plays a role in the regulation of metabolism, electrolyte balance, water balance, and the body′s stress response. It has been utilized in research to investigate the impact of inflammation and stress on cellular processes.