| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 53 | Human, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Cdc25C Rabbit Monoclonal Antibody detects endogenous levels of Cdc25C protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Cdc25C is a conserved protein that plays a key role in the regulation of cell division. Cdc25C plays a crucial role in regulating the cell cycle by acting as a phosphatase that activates cyclin-dependent kinases (Cdks), which are essential for the progression of the cell cycle. Specifically, Cdc25C dephosphorylates and activates Cdk2 and Cdc2, facilitating the transition from the G2 phase to mitosis. This activation is vital for proper cell division and DNA replication, as Cdc25C ensures that cells only enter mitosis when fully prepared, thereby maintaining genomic stability. Dysregulation of Cdc25C can lead to uncontrolled cell proliferation and is implicated in various cancers, making Cdc25C an important target for research and therapeutic interventions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562 cells, using Cdc25C Rabbit Monoclonal Antibody (EAB22186) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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