| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2a | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 17 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Stathmin/Op18 Mouse Monoclonal Antibody detects endogenous levels of Stathmin/Op18 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Op18 also known as oncoprotein 18, stathmin, STMN1 is a highly conserved, tubulin-associated intracellular phosphoprotein that plays a pivotal role in regulating microtubule dynamics. Op18′s ability to modulate microtubule stability is crucial for proper cell division and differentiation, making Op18 an essential player in various cellular processes. Notably, Op18 undergoes multiple post-translational modifications, including phosphorylation, which can significantly influence activity and interactions with other proteins. Such regulation is particularly important in cancer, as aberrant expression and modification of Op18 have been linked to various malignancies, including breast carcinomas and acute leukemias. Op18′s presence in these cancers underscores potential as a biomarker and therapeutic target, highlighting the importance of understanding Op18 function and regulation in both normal and pathological states. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, HepG2, NIH/3T3 cells, using Stathmin/Op18 Mouse Monoclonal Antibody (EAB21255) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human tonsil tissue, using Stathmin/Op18 Mouse Monoclonal Antibody (EAB21255) at 1:200 dilution.
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