| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 37 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IP=1:10-100 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | TRAP Rabbit Monoclonal Antibody detects endogenous levels of TRAP protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
TRAP(Tartrate resistant acid phosphatase) also known as ACP5 is an iron-containing glycoprotein that plays a crucial role in bone metabolism by catalyzing the hydrolysis of phosphate esters, TRAP is essential for bone resorption and remodeling. TRAP is primarily located in osteoclasts, the cells responsible for bone degradation, and TRAP activity is vital for maintaining bone homeostasis. TRAP regulation is particularly important in pathological conditions such as osteoporosis and certain cancers, where osteoclast activity is dysregulated. Additionally, receptor activator of NFkB ligand (RANKL) activates TRAP, which enhances osteoclast differentiation and function, further underscoring TRAP significance in bone health and disease. |
| Product Image Gallery | |
 Western blot analysis of extracts on MCF7, A549 cells, using TRAP Rabbit Monoclonal Antibody (EAB13433) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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