| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 83 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RSK3 Rabbit Monoclonal Antibody detects endogenous levels of RSK3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RSK3 also known as p90-RSK3, RPS6KA2 is a member of the ribosomal S6 kinase family. RSK3 plays a crucial role in cellular signaling pathways activated by receptor tyrosine kinases. One of the key functions of RSK3 is involvement in the regulation of cell growth and survival, particularly in response to mitogenic signals. This regulation is vital for normal cellular function and development, as dysregulation of RSK3 has been implicated in various diseases, including cancer. Dual kinase catalytic domains allow RSK3 to phosphorylate a range of substrates, thereby influencing multiple downstream signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, PC12, Jurkat cells, using RSK3 Rabbit Monoclonal Antibody (EAB21144) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 83 kDa; Observed band size: 90 kDa |
