| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IHC-P, IF/ICC, ELISA | 39 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:10000-50000 IHC-P=1:1000-5000 IF/ICC=1:200-1000 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | hnRNP A1 Mouse Monoclonal Antibody detects endogenous levels of hnRNP A1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
hnRNP A1 is a crucial member of the heterogeneous nuclear ribonucleoprotein (hnRNP) family. hnRNP A1 plays a significant role in mRNA transcription, pre-mRNA processing, and the transport of mature mRNA to the cytoplasm for translation. hnRNP A1 is primarily localized in the nucleus, where hnRNP A1 interacts with heterogeneous nuclear RNA (hnRNA) produced by RNA polymerase II, and is essential for the regulation of gene expression. hnRNP A1 influences splice site selection and antagonizes the association of splicing factors, thereby modulating pre-mRNA processing. hnRNP A1′s ability to shuttle between the nucleus and cytoplasm allows participation in various stages of mRNA metabolism, making hnRNP A1 vital for maintaining mRNA stability and proper gene expression. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, K562, Jurkat, HEK293 cells, using hnRNP A1 Mouse Monoclonal Antibody (EAB22827) at 1:20000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 39 kDa; Observed band size: 34 kDa |
