| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2a | Monoclonal | WB, IP, IHC-P, IF/ICC, FC, ELISA | 85 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:5000-20000 IP=1:100-500 IHC-P=1:500-2000 IF/ICC=1:200-1000 FC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CD71 Mouse Monoclonal Antibody detects endogenous levels of CD71 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CD71 also known as Transferrin Receptor, TR, TFR, TFRC is a type II membrane glycoprotein forming a disulfide-linked homodimer of two identical subunits. CD71 maintains iron homeostasis by binding to transferrin, a serum iron-transport protein, and facilitates cellular iron uptake through receptor-mediated endocytosis. CD71 expression remains high in proliferating cells, reticulocytes, and erythroid precursors, while staying absent in resting leukocytes but becoming upregulated upon activation of lymphocytes, monocytes, and macrophages. CD71 appears on most dividing cells and brain endothelium, showing significance in hematopoiesis and neurobiology. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Raji, HepG2, A431, U2OS cells, using CD71 Mouse Monoclonal Antibody (EAB22801) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
Predicted band size: 85 kDa; Observed band size: 90 kDa |
