| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2a | Monoclonal | WB, IHC-P, IF/ICC, FC, ELISA | 113 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Na+/K+ ATPase α1 Mouse Monoclonal Antibody detects endogenous levels of Na+/K+ ATPase α1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Na+/K+ ATPase α1 also known as α1 Sodium Potassium ATPase, ATP1A1 is a crucial plasma membrane protein responsible for maintaining the electrochemical gradients of sodium and potassium ions across the cell membrane. Located in the plasma membrane, Na+/K+ ATPase α1 plays an essential role in regulating cellular ion balance, which is vital for processes such as maintaining cell volume, establishing the resting membrane potential, and facilitating secondary active transport of various solutes. As a member of the P-type ATPase family, Na+/K+ ATPase α1 hydrolyzes ATP to drive the active transport of three sodium ions out of the cell and two potassium ions into the cell, thereby sustaining essential physiological functions including nerve impulse transmission, muscle contraction, and kidney function. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A431, HepG2 cells, using Na+/K+ ATPase α1 Mouse Monoclonal Antibody (EAB21157) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded human lung cancer tissue, using Na+/K+ ATPase α1 Mouse Monoclonal Antibody (EAB21157) at 1:200 dilution.
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