| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC, FC | 21 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 FC=1:10-100 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Prdx1 Rabbit Monoclonal Antibody detects endogenous levels of Prdx1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Prdx1 also known as PRX1, PRX I is a member of the peroxiredoxin family of antioxidant enzymes. Prdx1 is primarily localized in the cytoplasm, where Prdx1 interacts with thioredoxin to facilitate antioxidant activity, although Prdx1 can also be found in the nucleus and mitochondria under certain conditions. The human Prdx1 gene is expressed in multiple tissues, such as the liver, kidney, testis, lung, and nervous system, highlighting Prdx1′s importance in various physiological processes. Notably, elevated levels of Prdx1 have been associated with breast cancer progression and are implicated in the pathogenesis of Alzheimer′s disease and Down syndrome, indicating Prdx1′s potential as a biomarker for these conditions. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, MCF7, HepG2, Jurkat cells, using Prdx1 Rabbit Monoclonal Antibody (EAB22772) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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