| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | IHC-P, IF/ICC, ELISA | 99 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Progesterone Receptor/PR Mouse Monoclonal Antibody detects endogenous levels of PProgesterone Receptor/PR protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PR(Progesterone Receptor) is a vital nuclear hormone receptor located within the cell nucleus, where PR functions as a transcription factor to regulate gene expression in response to progesterone binding. Nuclear localization is crucial for PR′s role in controlling essential biological processes such as the menstrual cycle, maintenance of pregnancy, and development of reproductive tissues. PR exists in two main isoforms, PR-A and PR-B, which are transcribed from distinct promoters and exhibit different functional properties. PR-B primarily acts as a transcriptional activator, promoting expression of genes involved in cell growth, differentiation, and apoptosis, while PR-A functions as a transcriptional repressor, modulating activity of other steroid hormone receptors. |
| Product Image Gallery | |
 Immunohistochemical analysis of paraffin-embedded Human breast caricnoma tissue, using Progesterone Receptor/PR Mouse Monoclonal Antibody (EAB14023) at 1:500 dilution.
 Immunofluorescence analysis of Hela cell, using Progesterone Receptor/PR Mouse Monoclonal Antibody (EAB14023) at 1:100 dilution.
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