| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IHC-P, IF/ICC, FC, ELISA | 86 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:5000-20000 IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Stat4 Mouse Monoclonal Antibody detects endogenous levels of Stat4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Stat4 also known as Signal transducer and activator of transcription 4 is a member of the STAT family of transcription factors. Stat4 is primarily located in the cytoplasm and translocates to the nucleus upon activation by cytokines such as interleukin-12 (IL-12), where Stat4 functions as a transcription factor to regulate gene expression. This nuclear localization is essential for promoting the differentiation of naive T cells into Th1 cells, which are vital for orchestrating the body′s immune response against intracellular pathogens and in the development of autoimmune diseases. By mediating responses to cytokines, Stat4 plays a significant role in the regulation of inflammation, hematopoiesis, and the immune system′s ability to respond to infections. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, HepG2, HEK293 cells, using Stat4 Mouse Monoclonal Antibody (EAB22785) at 1:5000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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