| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IHC-P, IF/ICC | 14 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IHC-P=1:100-500 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | α-Synuclein Rabbit Monoclonal Antibody detects endogenous levels of α-Synuclein protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
α-synuclein is a pivotal protein primarily expressed in neuronal cell bodies and synapses, where α-synuclein plays a crucial role in synaptic regulation and neuronal plasticity, essential for maintaining proper brain function and facilitating communication between neurons. α-synuclein is deeply involved in synaptic vesicle trafficking and neurotransmitter release, processes vital for efficient neuronal signaling. α-synuclein is implicated in the pathogenesis of several neurodegenerative diseases, including Parkinson′s disease and Alzheimer′s disease, where abnormal aggregation is a hallmark of disease progression. Additionally, α-synuclein expression is modulated during hematopoietic cell differentiation, indicating broader significance in cellular processes beyond the nervous system. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mosue brain, Rat brain cells, using α-Synuclein Rabbit Monoclonal Antibody (EAB22776) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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