| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 84 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PKCε Rabbit Monoclonal Antibody detects endogenous levels of PKCε protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PKCε also known as PKC epsilon, PRKCE, PKCE is a family of serine-and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKCε protein is primarily located in the cytoplasm and can translocate to the plasma membrane upon activation, which is essential for function in mediating responses to growth factors and hormones. Such translocation allows PKCε protein to interact with various substrates and signaling molecules, thereby influencing processes such as apoptosis and inflammation. PKCε protein is involved in the modulation of gene expression and has been implicated in various diseases, including cancer and neurodegenerative disorders, making PKCε protein a significant target for therapeutic interventions. Specific activation by diacylglycerols and phorbol esters further underscores PKCε protein importance in cellular signaling and potential as a biomarker for disease states. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Mouse heart, Mouse skin cells, using PKCε Rabbit Monoclonal Antibody (EAB22340) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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