| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IP, IF/ICC | 63 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:1000-5000 IP=1:10-100 IF/ICC=1:100-500 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | PINK1 Rabbit Monoclonal Antibody detects endogenous levels of PINK1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
PINK1 is a crucial member of the serine/threonine protein kinase family and functions as a tumor suppressor. PINK1 is primarily localized in mitochondria, where PINK1 plays a vital role in maintaining mitochondrial integrity and function. PINK1′s presence in mitochondria helps protect cells from mitochondrial dysfunction, particularly during cellular stress, by phosphorylating mitochondrial proteins essential for energy production and apoptosis regulation. PINK1′s widespread expression in tissues such as testis, skeletal muscle, and heart underscores PINK1′s importance in various physiological processes, while lower expression in tissues like pancreas and brain highlights specialized roles in cellular health and disease. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells, using PINK1 Rabbit Monoclonal Antibody (EAB21492) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
|
