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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2b | Monoclonal | WB, IHC-P, FC, ELISA | 22 | Human |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RhoA Mouse Monoclonal Antibody detects endogenous levels of RhoA protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RhoA is a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades.RhoA plays a crucial role in regulating the actin cytoskeleton, which is essential for various cellular processes such as cell shape, motility, and division. Proper function of RhoA is vital for maintaining cellular integrity and facilitating communication between cells, particularly in response to external signals. Dysregulation of Rho A has been implicated in numerous diseases, including cancer, where altered signaling pathways can lead to increased cell migration and invasion. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, A431, MCF7, Jurkat cells, using RhoA Mouse Monoclonal Antibody (EAB22339) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
 Immunohistochemical analysis of paraffin-embedded Human gastric cancer tissue, using RhoA Mouse Monoclonal Antibody (EAB22339) at 1:200 dilution.
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