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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, ELISA | 86 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:500-2000 | |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Gelsolin Rabbit Polyclonal Antibody detects endogenous levels of Gelsolin protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
Gelsolin plays a crucial role in regulating actin filament dynamics, which is essential for various cellular processes, including motility, shape maintenance, and intracellular transport. By severing actin filaments in the presence of calcium, Gelsolin facilitates cytoskeleton remodeling, allowing cells to respond effectively to environmental cues. This dynamic regulation is particularly important in leukocytes and platelets, where actin rearrangement is vital for immune responses and clot formation. Gelsolin′s ability to exist in both secreted and intracellular forms highlights its versatility and importance in maintaining cellular homeostasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on HepG2, Mouse testis, Rat testis cells, using Gelsolin Rabbit Polyclonal Antibody (EAB12092) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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