| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Polyclonal | WB, IHC-P, IF/ICC, ELISA | 101 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-300 IF/ICC=1:50-300 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | Phospho-VAV2 (Tyr142) Rabbit Polyclonal Antibody detects endogenous levels of VAV2 protein only when phosphorylated at Tyr142. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Vav2 functions as a guanosine nucleotide exchange factor (GEF) for RhoG and RhoA-like GTPases, facilitating GDP to GTP exchange, which activates these GTPases involved in cytoskeletal dynamics, cell migration, and proliferation. Vav2 expression is restricted to hematopoietic cells, including erythroid, lymphoid, and myeloid lineages, suggesting a pivotal role in immune responses and hematopoiesis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela cells treated with TNF, using Phospho-VAV2 (Tyr142) Rabbit Polyclonal Antibody (EAB12075) at 1:1000 dilution. The lane on the left is blocked with the phospho peptide.
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