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| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG2a | Monoclonal | WB, IHC-P, IF/ICC | 36 | Human, Mouse, Rat |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB=1:5000-20000 IHC-P=1:200-1000 IF/ICC=1:200-1000 |
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| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | HuR/ELAVL1 Mouse Monoclonal Antibody detects endogenous levels of HuR/ELAVL1 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
HuR also known as ELAVL1 is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. plays a crucial role in post-transcriptional regulation of gene expression by binding to AU-rich elements in the 3′-untranslated region of target mRNAs. This interaction stabilizes mRNA transcripts that would otherwise be rapidly degraded, thereby influencing the expression levels of genes involved in critical cellular processes such as growth, differentiation, and response to stress. HuR protein is ubiquitously expressed and is often overexpressed in various tumors, highlighting importance in cancer biology. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, Jurkat, HEK293, MCF7, NIH/3T3 cells, using HuR/ELAVL1 Mouse Monoclonal Antibody (EAB22727) at 1:10000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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