| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P | 68 | Human, Mouse |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | CIP4 Rabbit Monoclonal Antibody detects endogenous levels of CIP4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
CIP4 also known as TRIP10 is a 601 amino acid protein that localizes to the cytoplasm and the cytoskeleton, as well as to the lysosome and the golgi apparatus and contains one FCH domain, one SH3 domain and one REM repeat. Expressed in a variety of tissues, including kidney, brain, liver, lung, heart and pancreas, CIP4 is required for the Insulin-dependent translocation of Glut4 to the plasma membrane and is essential for the coordination of membrane tubulation with Actin cytoskeletal reorganization during endocytosis. CIP4 exists as multiple alternative spliced isoforms and is subject to post-translational tyrosine phosphorylation. Aberrant splicing events during CIP4 transcription are associated with the pathogenesis of renal cell carcinoma, suggesting a role for CIP4 in tumor transformation and metastasis. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2 cells, using CIP4 Rabbit Monoclonal Antibody (EAB22170) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
Predicted band size: 68 kDa; Observed band size: 75 kDa |
