

| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | IHC-P, IF/ICC, FC, ELISA | 29 | Human, Mouse, Rat, Pig |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
IHC-P=1:100-500 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | POMC Mouse Monoclonal Antibody detects endogenous levels of POMC protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
POMC (pro-opiomelanocortin) also known as corticotropin-lipotropin is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific post-translational processing by prohormone convertases. POMC is cleaved into ten hormone chains named NPP, γ-MSH, ACTH, α-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin β, Lipotropin γ, β-MSH, β endorphin and Met-enkephalin. Defects in the gene that encodes POMC are the cause of POMC deficiency, which is characterized by red hair and adrenal insufficiency. Mutations in the POMC gene have also been linked to susceptibility to obesity. |
| Product Image Gallery | |
![]() Immunohistochemistry of paraffin-embedded Human pituitary tissue, using POMC Mouse Monoclonal Antibody (EAB22405) at 1:500 dilution.
![]() Immunofluorescence analysis of Hela cell, using POMC Mouse Monoclonal Antibody (EAB22405)(green) at 1:200 dilution.
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