DSS (CAS: 68528-80-3)
Catalog #：EBC51167
Biological Activity
Synonyms DSS; Disuccinimidyl octanedioate; DSS Crosslinker
Chemical Name Suberic acid bis(N-hydroxysuccinimide ester)
Application DSS is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)
CAS Number 68528-80-3
Purity ≥99.0%
Molecular Weight 368.34
Molecular Formula C16H20N2O8
SMILES C1CC(=O)N(C1=O)OC(=O)CCCCCCC(=O)ON2C(=O)CCC2=O
Target & IC50 Non-cleavable Linker
Shipping Gel Pack
Storage Store at -20°C
Preparing Stock Solutions Molecular Structure
ConcentrationSolventMass 1 mg 5 mg 10 mg
1 mM 2.7149 ml 13.5744 ml 27.1488 ml
5 mM 0.5430 ml 2.7149 ml 5.4298 ml
10 mM 0.2715 ml 1.3574 ml 2.7149 ml
50 mM 0.0543 ml 0.2715 ml 0.5430 ml
Solubility
DMSO: 250mg/mL (678.72 mM)
Product Description

DSS is a homobifunctional amine-reactive crosslinker. It is usually coupled to molecules containing primary amines via amide bonds buffered at pH 7.5 (6.5-8.5). It incorporates an 8-atom spacer arm. 
For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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