| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Rabbit IgG | Monoclonal | WB, IHC-P, IF/ICC | 27 | Human, Mouse, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IHC-P=1:50-200 IF/ICC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | RPS3 Rabbit Monoclonal Antibody detects endogenous levels of RPS3 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
RPS3(Ribosomal protein S3) is a ribosomal protein that is a component of the 40S subunit, where it forms part of the domain where translation is initiated. RPS3 plays a significant role in translation and ribosome maturation. RPS3 mediates the formation of the mRNA binding site located 3′ of the codon in the decoding site, which is essential for accurate protein synthesis. RPS3 also participates in DNA damage recognition, demonstrating a strong affinity for abasic sites and 7,8-dihydro-8-oxoguanine residues. This interaction supports base excision repair processes, as RPS3 collaborates with human base excision repair proteins such as OGG1 and Ref-1, highlighting RPS3′s importance not only in ribosomal function but also in maintaining genomic integrity. Nuclear export of ribosomal subunits, including RPS3, is a highly regulated, energy-dependent process, underscoring RPS3′s significance in cellular function and potential implications in various biological processes and diseases. |
| Product Image Gallery | |
 Western blot analysis of extracts on Hela, HepG2, Jurkat cells, using RPS3 Rabbit Monoclonal Antibody (EAB22450) at 1:1000 dilution. Secondary antibody Goat Anti-Rabbit IgG (H&L)-HRP (EAB21002) at 1:5000 dilution.
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