Phospho-RIP/RIPK1 (Ser161) Mouse Monoclonal Antibody
Catalog #:EAB22753
Host / Isotype Clonality Applications MW (kDa) Reactivity
Mouse IgG1 Monoclonal WB 76 Human
Applications Dilutions
The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user.
WB=1:500-2000
Application Key

WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin
IF
-Immunofluorescence ICC-Immunocytochemistry FC-Flow Cytometry

Reactivity Key

H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish
Hr
-Horse All-All Species Expected

Product Information
Conjugate Unconjugate
Specificity Phospho-RIP/RIPK1 (Ser161) Mouse Monoclonal Antibody detects endogenous levels of RIP/RIPK1 protein only when phosphorylated at Ser161.
Purification Affinity purification
Concentration 1mg/ml
Format Liquid
Formulation In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol.
Shipping Gel Pack
Storage Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks.
UniProt ID

Q13546

Entrez Gene ID

8737

Product Description

RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases. The encoded protein plays a role in inflammation and cell death in response to tissue damage, pathogen recognition, and as part of developmental regulation. RIPK1/RIPK3 kinase-mediated necrosis is referred to as necroptosis. Genetic disruption of this gene in mice results in death shortly after birth. 

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For Research Use Only, Not For Diagnostic Or Therapeutic Procedures.
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