| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, FC, ELISA | 31 | Human |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BAFF Mouse Monoclonal Antibody detects endogenous levels of BAFF protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BAFF also known as TALL-1, TNFSF13B is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family and plays a pivotal role in immune regulation. BAFF is predominantly expressed in peripheral blood leukocytes, monocytes, and macrophages, where BAFF is essential for modulating infections, inflammation, autoimmune diseases, and tissue homeostasis. BAFF functions as a potent B cell stimulatory factor, significantly influencing B cell proliferation and serving as a key mediator in B cell-associated autoimmune disorders. BAFF′s structure features a C-terminal extracellular domain with a jelly roll topography, which is crucial for ligand trimerization. The interaction between BAFF and its receptor triggers oligomerization, leading to the initiation of downstream signaling pathways. |
| Product Image Gallery | |
 Western blot analysis of extracts on Molt-4, SKNSH cells, using BAFF Mouse Monoclonal Antibody (EAB21741) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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