| Host / Isotype | Clonality | Applications | MW (kDa) | Reactivity |
| Mouse IgG1 | Monoclonal | WB, IF/ICC, FC, ELISA | 46 | Human, Rat |
| Application Key | WB-Western Blot IP-Immunoprecipitation IHC-Immunohistochemistry IHC-P-Immunohistochemistry-Paraffin |
| Reactivity Key | H-Human M-Mouse R-Rat Mk-Monkey B-Bovine Pg-Pig Hm-Hamster Dg-Dog C-Chicken X-Xenopus Z-Zebrafish |
| Applications Dilutions | |
| The application notes include recommended starting dilutions;optimal dilutions/concentrations should be detemined by the end user. | |
| WB(Westem Blotting) IHC-P(Immunohistochemistry-Paraffin) IF/ICC(Immunofluorescence/Immunocytochemistry) ELISA(Enzyme-linked Immunosorbent Assay) |
WB=1:500-2000 IF/ICC=1:100-500 FC=1:50-200 |
| Product Information | |
| Conjugate | Unconjugate |
| Specificity | BMP4 Mouse Monoclonal Antibody detects endogenous levels of BMP4 protein. |
| Purification | Affinity purification |
| Concentration | 1mg/ml |
| Format | Liquid |
| Formulation | In PBS, pH 7.4, containing 0.02% sodium azide,0.5% BSA and 50% glycerol. |
| Shipping | Gel Pack |
| Storage | Store at -20°C least 1 year from the date of shipment. avoid repeated freeze/thaw cycles. Aliquots may be stored at +4°C for 1-2 weeks. |
| UniProt ID | |
| Entrez Gene ID | |
| Product Description | |
BMP4 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. BMP4 plays a crucial role in regulating bone and cartilage development. BMP4 is primarily located in the extracellular matrix and is secreted by various cell types, where BMP4 interacts with specific receptors to initiate signaling pathways that lead to cellular differentiation and tissue formation. BMP4 is involved in activating the Smad signaling pathway, which is essential for mediating BMP effects on gene expression. BMP4′s ability to induce cartilage and bone formation highlights BMP4′s importance in developmental biology and regenerative medicine, making BMP4 a significant target for research into skeletal disorders and tissue engineering applications. |
| Product Image Gallery | |
 Western blot analysis of extracts on A549, HepG2, C6 cells, using BMP4 Mouse Monoclonal Antibody (EAB22481) at 1:1000 dilution. Secondary antibody Goat Anti-Mouse IgG (H&L)-HRP (EAB21001) at 1:5000 dilution.
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